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Faculty
There are 24 full faculty in
the Neuroscience Graduate Program. They come from 6
departments of Loyola and from Hines VA Hospital.
Expertise is present in a
number of research areas, including
- neurodegenerative
diseases and neurotoxity (Battaglia, Collins,
Druse-Manteuffel, Jones, Lee, Neafsey, Piedras-Renteria)
- neuroendocrinology and
the autonomic nervous system (DonCarlos, McNulty,
Neafsey, Pak, Scrogin, Simmons, Walter)
- cellular
electrophysiology (Cukierman, Konopka,
Piedras-Renteria)
- neurochemistry and
neuropharmacology (Battaglia, Collins, DonCarlos,
Druse-Manteuffel, Lee, Simmons)
- neuroimmunology (Janusek,
Jones, McNulty, Matthews, Stubbs, White)
- CNS/PNS injury and
repair (Castro, Jones, Kartje, Stubbs, White)
- neuroplasticity and
development (Castro, Jones, Kartje, Neafsey, Pak,
Walter, White)
- brain and behavior
(Castro, DonCarlos, Gray, Kartje, Konopka, Neafsey, Pak)
- circulatory shock
(Scrogin)
- application of
non-linear dynamics mathematics to analysis of
biological signals and biological information in general
(Webber)
- myelination and
demyelinating diseases (Stubbs, Jones)
Methodologies in use
include neuroanatomy, immunocytochemistry, in situ
hybridization, c-fos mapping of regional functional activity
patterns, neurotransmitter receptor binding and
autoradiography, steroid receptor autoradiography, HPLC,
GC/MS, cell culture, confocal microscopy, evoked potentials,
single unit recording, intracellular recording, voltage and
patch clamping, behavioral analysis, uptake of radioactive
neurotransmitters, electron microscopy, various immune
system assays, iontophoresis, enzymatic analysis, DNA
microarrays, and Northern, Southern, and Western blots.
This faculty is distinguished
not only by its breadth of interests and research expertise
but also by its commitment to graduate education. Advisors
and Ph.D. Committee members interact with students
and are committed to their growth and development. They are
readily accessible, their doors are always open.
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George Battaglia
- Professor of
Pharmacology
Ph.D. in Pharmacology, University of Toronto, 1983
prenatal drug effects on postnatal serotonin and
monoamine pathways; neurochemical effects of drugs of
abuse and drug-induced neurotoxicity; receptor-effector
regulatory responses to therapeutic drugs.
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Anthony J. Castro
- Professor of Cell
Biology, Neurobiology & Anatomy
Ph.D. in Anatomy, University of Florida, 1970
plasticity of motor system pathways after brain or
spinal cord damage in the newborn rat; use of fetal
neocortical transplants in repair of brain damage.
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Michael A. Collins
- Professor of Cellular
and Molecular Biochemistry
Ph.D. in Chemistry, Purdue, 1968
neurotoxicity of ethanol and beta-carbolines; ethanol
neuroprotection.
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Samuel Cukierman
- Associate Professor of
Physiology
M.D., Ph.D in Physiology, Fed. Univ. of Rio de Janiero,
1982
biophysical properties and the physiological roles of
ion channels; investigation of electrostatic potentials
modulating the gating of nerve sodium channels;
modulation of nerve sodium channels by different protein
kinases and lipid metabolites; structure-function
relationships of cerebellum IP3-activated calcium
channels; potassium currents for cell proliferation.
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Lydia L. DonCarlos
- Professor of Cell
Biology, Neurobiology & Anatomy
Ph.D. in Neurobiology, Kent State University, 1985
neuroanatomy and neurochemistry of circuits involved in
reproductive behavior and physiology; steroid receptor
distribution and regulation; sexual differentiation of
the brain; gonadal steroid effects on neural function
neural control of reproductive behavior; estrogen and
progesterone receptor localization.
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Mary Druse (Manteuffel)
- Professor of Cellular
and Molecular Biochemistry
Ph.D. in Biochemistry, University of North Carolina,
1972
fetal alcohol effects on serotonergic and dopaminergic
innervation of the cerebral cortex; aging and alcohol
effect on the mesolimbic and nigrostriatal dopamine
systems.
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Linda Janusek
- Professor, Marcella
Niehoff School of Nursing
Ph.D. in Physiology, University of Illinois at Chicago,
1978
psychneuroimmunology of stress in cancer.
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Kathryn Jones
- Professor of Cell
Biology, Neurobiology & Anatomy
Ph.D. in Anatomy, University of Illinois at Chicago,
1983
molecular basis for neural survival and regeneration
after injury; therapeutic role of steroid hormones in
regeneration.
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Gwendolyn Kartje
- Hines VA--Neurology,
Associate Professor of Neurology and of Cell Biology,
Neurobiology & Anatomy
Ph.D. in Anatomy, Loyola University Chicago, 1984; M.D.,
Loyola University Chicago, 1988
plasticity of the nervous system, recovery from injury,
neuronal transplants, neuronal growth factors and growth
inhibiting factors such as Nogo-A.
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John M. Lee
- Professor of Pathology
and Pharmacology
Ph.D. (1983) in Physiology and Biophysics and M.D.
(1988), University of Illinois Chicago
clinicopathological correlations of neurodegenerative
diseases; animal models of dementia and movement
disorders; neurotransmitter receptor/effector coupling
mechanisms in aging and Alzheimer's disease; gene
expression profiles in Alzheimer's disease; Director of
Loyola Brain Bank, Chair of Pathology
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Susan McGuire
- Assistant Professor of
Pathology
Ph.D. in Nutritional Sciences, University of Missouri
(Columbia), 1995
neural signaling pathways that, altered during aging,
predispose and individual to age-related
neurodegenerative diseases such as Parkinson's disease
(PD) or Alzheimer's disease (AD).
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John A. McNulty
- Professor of Cell
Biology, Neurobiology & Anatomy
Ph.D. in Biology, USC, 1976
comparative ultrastructure and biochemistry of the
pineal gland as related to photoneuroendocrine
transduction and secretion; neuroimmunology and the role
of microglia; circadian and circannual rhythms.
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Herb L. Matthews
- Professor of
Microbiology and Immunology
Ph.D. in Microbiology, West Virginia University, 1977
stress and immunity; psychoneuroimmunology; breast and
prostate cancer; natural killer cell function
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Edward J. Neafsey
- Professor of Cell
Biology, Neurobiology & Anatomy
Ph.D. in Anatomy, UCLA, 1976
Director, Neuroscience Graduate Program
cerebral cortical and hippocampal control of
cardiovascular responses to emotional stress; MPTP model
of Parkinson's disease; electrophysiology of neuronal
transplants; neurotoxicity of ethanol and HIV-gp120.
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Toni Pak
- Assistant Professor of
Cell Biology, Neurobiology & Anatomy
Ph.D. in Neuroscience, University of Colorado (Boulder),
2002
neuroendocrine regulation of puberty; molecular
mechanisms of nuclear steroid receptor function
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Erika Piedras-Renteria
- Associate Professor of
Physiology
Ph.D. in Physiology, University of Illinois
Urbana-Champaign, 1996
molecular mechanisms of neuronal P/Q calcium channel
function in normal and diseased states, especially
spinocerebellar ataxia type 6 (SCA6)
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Karie Scrogin
- Associate Professor of
Pharmacology
Ph.D. in Behavioral Neuroscience, Oregon Health Sciences
University, 1992
role of central serotonin in reflex control of
circulation after hemorrhage
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William H. Simmons
- Professor of Molecular
and Cellular Biochemistry
Ph.D. in Physiology, University of Illinois, 1979
identification and purification of peptidases involved
in neuropeptide metabolism in brain.
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Evan Stubbs
- Associate Professor of
Neurology and Molecular and Cellular Biochemistry
Ph.D. in Biochemistry, University of Missouri, 1987
neurochemistry and immunology of polyneuropathies;
phosphotidyl inositol second messenger signaling.
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James S. Walter
- Associate Professor of
Urology
Ph.D. in Physiology, University of Health
Sciences/Chicago Medical School, 1982
bladder, bowel, and respiratory problems following
spinal cord injury; neural prosthetics; diagnostic
techniques for the autonomic nervous system.
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Charles L. Webber, Jr.
- Professor of Physiology
Ph.D. in Physiology, Loyola University of Chicago, 1974
chaotic and nondeterministic dynamics of neural systems;
integrated function of mammalian cardiopulmonary control
systems.
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Fletcher White
- Assistant Professor of
Cell Biology, Neurobiology & Anatomy
Ph.D. in Anatomy, Medical College of Ohio, 1995
neuroanatomical plasticity in the spinal cord,
particularly as related to pain transmission after
peripheral nerve injury.
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